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CALSCALE:GREGORIAN
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X-WR-CALNAME:Perfusion Education
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X-WR-CALDESC:Events for Perfusion Education
BEGIN:VEVENT
SUMMARY:ECMO Platform Overview. Acute Hypoxemic Respiratory Failure. Atrial
Septal Defects
DTSTART:20210602T064500
DTEND:20210602T084500
UID:2026-04-06-15-10-05@perfusioneducation.com
DTSTAMP:20260406T151005
DESCRIPTION:Vanderbilt University Medical Center\; Department of CV Surg
ery: Faculty Forum \;- ECMO platform overview: Cost\, safety\, ver
satility \;Tammy Sparacino Journal Club: Lower or Higher O
xygenation Targets for Acute Hypoxemic Respiratory Failure \;
"BACKGROUND\nPatients with acute hypoxemic respiratory failure in the in
tensive care unit (ICU) are treated with supplemental oxygen\, but the ben
efits and harms of different oxygenation targets are unclear. We hypothesi
zed that using a lower target for partial pressure of arterial oxygen (Pao
2) would result in lower mortality than using a higher target. \nMETHODS:
In this multicenter trial\, we randomly assigned 2928 adult patients who h
ad recently been admitted to the ICU (≤12 hours before randomization) an
d who were receiving at least 10 liters of oxygen per minute in an open sy
stem or had a fraction of inspired oxygen of at least 0.50 in a closed sys
tem to receive oxygen therapy targeting a Pao2 of either 60 mm Hg (lower-o
xygenation group) or 90 mm Hg (higher-oxygenation group) for a maximum of
90 days. The primary outcome was death within 90 days.\nRESULTS\nAt 90 day
s\, 618 of 1441 patients (42.9%) in the lower-oxygenation group and 613 of
1447 patients (42.4%) in the higher-oxygenation group had died (adjusted
risk ratio\, 1.02\; 95% confidence interval\, 0.94 to 1.11\; P=0.64). At 9
0 days\, there was no significant between-group difference in the percenta
ge of days that patients were alive without life support or in the percent
age of days they were alive after hospital discharge. The percentages of p
atients who had new episodes of shock\, myocardial ischemia\, ischemic str
oke\, or intestinal ischemia were similar in the two groups (P=0.24).\nCON
CLUSIONS\nAmong adult patients with acute hypoxemic respiratory failure in
the ICU\, a lower oxygenation target did not result in lower mortality th
an a higher target at 90 days. (Funded by the Innovation Fund Denmark and
others" \;John Ingram Knowledge Nuggets: Atrial Sept
al Defects \;
ORGANIZER;CN="MediWeb Perfusion Education":MAILTO:contact@perfusioneducatio
n.com
LOCATION:MediWeb Studio – Perfusion Meeting 2020\, 123 Ruel Ln\, Magnolia
\, TX\, 77355\, United States
CATEGORIES:Perfusion Meeting 2020
ATTACH;FMTTYPE=image/jpeg:https://library.perfusioneducation.com/img/youtub
e/medium/dgeZU7zQ4UA.jpg
URL:https://arch.perfusioneducation.com/video/ecmo-platform-overview-acute-
hypoxemic-respiratory-failure-atrial-septal-defects
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